Selected Publications
  1. Laurans L, Chajadine M, Mouttoulingam N, Lavelle A, Bacquer E, Suffee N, Esposito B, Melhem NJ, Le Goff W, Haddad Y, Paul JLP, Rainteau D, Tedgui A,  Ait-Oufella H, Zitvogel L,  Sokol H, TALEB S. Obesogenic diet increases atherosclerosis through promoting microbiota dysbiosis-induced gut lymphocyte trafficking into the periphery. Cell Rep. 2023 Oct 27;42(11):113350. doi: 10.1016/j.celrep.2023.113350. 
  2. Melhem NJ, Chajadine M, Gomez I, Howangyin KY, Bouvet M, Knosp C, Sun Y, Rouanet M, Laurans L, Cazorla O, Lemitre M, Vilar J, Mallat Z, Tedgui A, Ait-Oufella H, Hulot JS, Callebert J, Launay JM, Fauconnier J, Silvestre JS, TALEB S. Endothelial Cell Indoleamine 2, 3-Dioxygenase 1 Alters Cardiac Function Following Myocardial Infarction Through Kynurenine.  Circulation. 2021;143:566–580.  DOI: 10.1161/CIRCULATIONAHA.120.050301
  3. Laurans L, Venteclef N, Haddad Y, Chajadine M, Alzaid F, Metghalchi S, Sovran B, Denis RGP, Dairou J, Cardellini M, Moreno-Navarrete JM, Straub M, Jegou S, McQuitty C, Viel T, Esposito B, Tavitian B, Callebert J, Luquet SH, Federici M, Fernandez-Real JM, Burcelin R, Launay JM, Tedgui A, Mallat Z, Sokol H, TALEB S. Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health. Nat Med. 2018 Aug;24(8):1113-1120
  4. Metghalchi S, Vandestienne M, Haddad Y, Esposito B, Dairou J, Tedgui A, Mallat Z, Potteaux S, TALEB S. Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet. PLoS One. 2018 Mar 1;13(3):e0193737
  5. Clément M, Haddad Y, Raffort J, Lareyre F, Newland SA, Master L, Harrison J, Ozsvar-Kozma M, Bruneval P, Binder CJ, TALEB S, Mallat Z. Deletion of IRF8 (Interferon Regulatory Factor 8)-Dependent Dendritic Cells Abrogates Proatherogenic Adaptive Immunity. Circ Res. 2018 Mar 16;122(6):813-820
  6. Haddad Y, Lahoute C, Clément M, Laurans L, Metghalchi S, Zeboudj L, Giraud A, Loyer X, Vandestienne M, Wain-Hobson J, Esposito B, Potteaux S, Ait-Oufella H, Tedgui A, Mallat Z, TALEB S. The Dendritic Cell Receptor DNGR-1 Promotes the Development of Atherosclerosis in Mice. Circ Res. 2017 Jul 21;121(3):234-243
  7. Metghalchi S, Ponnuswamy P, Simon T, Haddad Y, Laurans L, Clément M, Dalloz M, Romain M, Esposito B, Koropoulis V, Lamas B, Paul JL, Cottin Y, Kotti S, Bruneval P, Callebert J, den Ruijter H, Launay JM, Danchin N, Sokol H, Tedgui A, TALEB S*, Mallat Z*. Cell Metab. 2015 Sep 1;22(3):460-71 (*co-last authors)
  8. Romain M*, TALEB S*, Dalloz M, Ponnuswamy P, Esposito B, Pérez N, Wang Y, Yoshimura A, Tedgui A, Mallat Z. Overexpression of SOCS3 in T lymphocytes leads to impaired interleukin-17 production and severe aortic aneurysm formation in mice. Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):581-4 (*co-first authors)
  9. Simon T, TALEB S, Danchin N, Laurans L, Rousseau B, Cattan S, Montely JM, Dubourg O, Tedgui A, Kotti S, Mallat Z. Circulating levels of interleukin-17 and cardiovascular outcomes in patients with acute myocardial infarction. Eur Heart J. 2013 Feb;34(8):570-7
  10. Chandesris MO*, Azarine A*, Ong KT*, TALEB S*, Boutouyrie P, Mousseaux E, Romain M, Bozec E, Laurent S, Boddaert N, Thumerelle C, Tillie-Leblond I, Hoarau C, Lebranchu Y, Aladjidi N, Tron F, Barlogis V, Body G, Munzer M, Jaussaud R, Suarez F, Clément O, Hermine O, Tedgui A, Lortholary O, Picard C, Mallat Z, Fischer A. Frequent and widespread vascular abnormalities in human signal transducer and activator of transcription 3 deficiency. Circ Cardiovasc Genet. 2012 Feb 1;5(1):25-34 (*co-first authors)
  11. TALEB S, Romain M, Ramkhelawon B, Uyttenhove C, Pasterkamp G, Herbin O, Esposito B, Perez N, Yasukawa H, Van Snick J, Yoshimura A, Tedgui A, Mallat Z. J Exp Med. 2009 Sep 28;206(10):2067-77.
  12. TALEB S, Herbin O, Ait-Oufella H, Verreth W, Gourdy P, Barateau V, Merval R, Esposito B, Clément K, Holvoet P, Tedgui A, Mallat Z. Defective leptin/leptin receptor signaling improves regulatory T cell immune response and protects mice from atherosclerosis. Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2691-8